Recurrent Breast Cancer

Wednesday, September 23, 2015








Women who will be pregnant during flu season; adults fifty and older; children with pulmonary (lung) disease, such as asthma; those with heart, kidney, and liver disease; and adults and children with weakened immune systems (i.e., HIV infection) should be immunized.

People who live in nursing homes or care facilities, those who live with someone at high risk of flu complications, caregivers, children under six months of age, and health care workers should all get the vaccine.
FluMist spray is recommended for healthy children two through eight years of age.
Those who shouldn't get the spray vaccine include children less than two years of age; adults; children or adults who have heart disease, diabetes, kidney disease; and Guillan-Barre Syndrome, a condition that includes a weakened immune system.
Anyone with a history of severe allergic reaction to eggs or complications from prior a previous flu vaccination, pregnant women, and those who have a weakened immune system due to a stem cell transplant should not get the vaccine. The vaccine is safe for those who have a suppressed immune system, such as those with diabetes or HIV.
FluMist, the nasal spray, is easy to administer. Children and adults might prefer it to the injection. Children ages two to eight have better immunity with FluMist than the injection.
The highest priority for flu vaccine includes children between six months and eighteen years old, children on long-term aspirin therapy, women who will be pregnant during flu season, adults fifty and older, and children with diseases of the lungs, such as asthma.
The injectable vaccine can cause muscle aches and fever for one to two days. Possible side effects of the inhaled vaccine include runny nose, headache, and sore throat. It takes two weeks for the flu vaccine to take effect. Lowering flu risk includes washing hands with soap and water, using alcohol based sanitizer on the hands, avoid touching eyes, nose or mouth whenever possible, and avoiding crowds when the flu is prevalent.


The American military experience in World War I and the influenza pandemic in 1918 were closely intertwined. The war fostered influenza in the crowded conditions on the Western Front The flu virus
traveled with military personnel from camp to camp and across the Atlantic. At the height of American military involvement in WW2, September through November 1918, influenza and pneumonia sickened twenty to forty percent of Navy and Army personnel and rendered hundreds of thousands of military personnel non-effective.

During the American Expeditionary Forces' campaign at Meuse-Argonne, the flu epidemic diverted urgently needed resources from combat support to transporting and caring for the sick and the dead. Influenza and pneumonia killed more American soldiers and sailors during the war than did enemy weapons.

Autumn is coming. The CDC (Centers for Disease Control) recommends everyone six months and older be immunized against the flu, unless there is a medical reason not to. Those who are two to forty nine years of age need the annual flu vaccine.

Flu season begins early October and lasts through May. Those who receive the vaccine have protection two weeks after receiving it. The vaccine can be given by either injection or inhalation.

 Most people have no side significant effects. Low grade fever and soreness at the injection site could occur. The inhaled nasal spray might cause runny nose, headache, fatigue, and mild fever. These symptoms resolve in a few days. The vaccine is sixty to seventy percent effective in preventing the flu.

The U.S. Centers for Disease Control (CDC) recommends the nasal spray instead of the injection for children between two and eight. The spray might cause mild runny nose, headache, cough, and sore throat. These symptoms are temporary and are milder than the flu. Those who choose the inhaled vaccine, FluMist, could have similar symptoms which are not caused by the flu.  Those who receive the injection don't need the inhaled spray.
Children and adults might prefer the inhaled spray instead of the injection. Kids two to eight years of age have a better response with the spray.  

High priority for receiving the vaccine include children and young adults between six months and eighteen years, and children on long-term aspirin for Reye’s Syndrome, a rare condition that causes swelling in the liver and brain after getting the flu.
 Women who will be pregnant during flu season; adults fifty and older; children with pulmonary (lung) disease, such as asthma; those with heart, kidney, and liver disease; and adults and children with weakened immune systems (i.e., HIV infection) should all be immunized.
 People who live in nursing homes or care facilities, those who live with someone at high risk of flu complications, caregivers, children under six months of age, and health care workers should get the vaccine.
FluMist spray is recommended for healthy children two through eight years of age.
Those who shouldn't get the spray vaccine include children less than two years of age, adults, children or adults who have heart disease, diabetes and kidney disease, and Guillan-Barre Syndrome, a condition of weakened immunity.  
Anyone with a history of severe allergic reaction to eggs or complications from prior a previous flu vaccination, pregnant women, and those who have a weakened immune system due to a stem cell transplant should not get the vaccine. The vaccine is safe for those who have a suppressed immune system, such as those with diabetes or HIV.
FluMist, the nasal spray, is easy to administer. Children and adults might prefer it to the injection. Children ages two to eight have better immunity with FluMist than the injection.
The highest priority for flu vaccine includes children between six months and eighteen years old, children on long-term aspirin therapy, women who will be pregnant during flu season, adults fifty and older, and children with diseases of the lungs, such as asthma.
The injectable vaccine can cause muscle aches and fever for one to two days. Possible side effects of the inhaled vaccine include runny nose, headache, and sore throat. It takes two weeks for the vaccine to take effect. Lowering flu risk includes washing hands with soap and water, using alcohol based sanitizer on the hands, avoid touching eyes, nose or mouth whenever possible, and avoiding crowds when the flu is prevalent.

The American military experience in World War I and the influenza pandemic in 1918 were closely intertwined. The war fostered influenza in the crowded conditions on the Western Front The flu virus
traveled with military personnel from camp to camp and across the Atlantic. At the height of American military involvement in WW2, September through November 1918, influenza and pneumonia sickened twenty to forty percent of Navy and Army personnel and rendered hundreds of thousands of military personnel non-effective.

During the American Expeditionary Forces' campaign at Meuse-Argonne, the flu epidemic diverted urgently needed resources from combat support to transporting and caring for the sick and the dead. Influenza and pneumonia killed more American soldiers and sailors during the war than did enemy weapons.

Tuesday, August 25, 2015


Paralysis Agitans

     I finished an examination on a seventy-year old retired sergeant. I was about to reassure him with a clean bill of health. I handed him his refill prescription. His hand tremored. The slip of paper fluttered to the floor.  

      One million people in the US and seven to ten million people worldwide live with Parkinson’s disease (PD). An estimated four percent are diagnosed before age fifty. If a person’s parent has PD, his or her chance of developing it is higher than those in the general population. Those with an affected first-degree relative have a four to nine percent higher chance of developing PD. Men are more likely to have it than women. The cause is unknown.
            
       PD is a chronic and progressive movement disorder. Symptoms such as tremor of the hands, arms, legs, jaw, and face increase over time. Slow movement (bradykinesia), muscle rigidity, stiffness, and impaired balance are characteristic. Activities such as getting out of bed unaided and driving can become challenging. Those affected might stop working due to symptom progression. Though FD is not considered fatal, in some cases, people could die due to complications, such as pneumonia.
        Brain neurons produce dopamine, a neurotransmitter that sends messages to the brain. Dopamine facilitates movement and coordination. Protein alpha-synuclein (Lewy Bodies) are present in the mid-brain stem and Olfactory Bulb. These regions correlate with impaired motor functions, such as disrupted smell and sleep disturbance. As PD progresses, dopamine decreases. There is no accurate diagnostic test. The diagnoses should be made by an experienced neurologist. Physicians rely on a neurological examination and the patient’s descriptions of symptoms to verify the diagnosis.
    
     Though there is no specific treatment, Levodopa is the most prescribed medication. Medication costs for one person with PD average $2,500 per year. Surgical options, such as deep brain stimulation, could alleviate symptoms. Surgery is effective for a small group of those affected and must meet specific criteria. Therapeutic surgery could cost up to $100,000 but is still in experimental stages. Over the last decade, the National Institutes of Health devoted significant resources to clinical trials. 
     Those who are affected who want to participate in clinical trials should log on to http://www.webmd.com/parkinsons-disease/guide/clinical-trials-parkinsons. The website provides a listing of trials that are open for enrollment.

       Those who have PD suffer anger and guilt. However,those affected may have a sense of relief that symptoms were unexplained or misdiagnosed for years. According to one patient, “the worst day of this was the day I was diagnosed. The best was when I understood that I could do something about it. It gave me control.”
       
      A crisis may be looming as the population ages. Combined direct and indirect cost of PD, including treatment, social security payments and lost income from inability to work are estimated at twenty five billion dollars per year.
                
Quote: “involuntary tremulous motion, with lessened muscular power, in parts not in action and even when supported, with a propensity to bend the trunk forward, and to pass from a walking to a running pace, the senses and intellects being uninjured.” James Parkinson 1817

 Questions or comments? Contact Dr. Clem at clement.hanson@gmail.com

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Wednesday, July 15, 2015




3-13-14

 
I was re-organizing my files today when I came across a Wall Street Journal article describing a woman’s predicament following a diagnosis of Alzheimer’s disease. The story, “Curse of a Diagnosis,” detailed her perilous journey through brain imaging, spinal fluid analysis, and imaging tests. Her husband commented, “There’s no way this diagnosis benefits people who have it”, and allowing his wife to be tested “was the biggest mistake of my life … a bomb has gone off ….”  He acknowledged that his wife “sometimes gets confused and repeats herself. But why not me; I eat right, exercise, and no one else in my family has this.” The couple owns an import saddle business in California. To add to the couple’s misfortune, she had to relinquish her driver’s license by California regulation.


This story, though not uncommon, touches my soul. The most compelling dimension of the article is what it doesn’t cover.

Let's put aside this woman’s unhappy situation for a few moments and look at the subject matter from another dimension. A healthy lifestyle that includes exercise, strong family and social connections, and dietary changes can delay and may prevent most chronic disease, including Alzheimer’s. A through medical evaluation is mandatory before we label someone with the “A-word.” Health conditions that act like Alzheimer’s are lengthy -- chronic heart disease, endocrine problems, Vitamin B12 deficiency, heart disease, uncontrolled diabetes, multiple sclerosis, depression, stroke, mini-stroke (transient ischemic attack), Lyme Disease, pesticide exposure, traumatic brain Injury, and medication side effects. 

Now consider a healthy lifestyle approach. Anti-oxidants, such as pomegranates, avocado, fish, turmeric, cinnamon, and alcohol/caffeine in moderation can improve memory and long term brain function. Regular exercise, such as walking, dancing, Tai Chi, and golf relieve stress, improve concentration and balance, sharpen the mind, and enhance blood flow to the brain. In other words, what’s good for the brain is good for the heart.

Neurocognitive rehabilitation can help with mental focus, memory recall, name recognition, and abstract reasoning. Two excellent references on healthy brain strategies include The Alzheimer’s Prevention Program, Keep your Brain Health for the Rest of Your Life (Small and Vorgan, Workman Publishing), and Neuropsychological Rehabilitation, Theory, Models, Therapy,and Outcome (Wilson, Gracey, Evans, and Bateman).     

There are numerous peripheral issues regarding treatment and evaluation of memory impairment, including insurance coverage and Social Security Disability.  Finally the medical term, “dementia,” evokes images of insanity, derangement, idiocy, and lunacy. In my opinion, we should avoid the “dementia” when referring to memory impairment and use, “mild cognitive impairment,” and “organic brain dysfunction of the Alzheimer’s’ type.”

It’s time to show optimism regarding Alzheimer’s evaluation and treatment. More diagnostic and  treatment strategies are on the horizon. Alzheimer’s is not a death sentence.
                                                                                                                                                                               Clement Hanson D.O. MPH












Friday, May 22, 2015

cataracts

Insomnia is a condition of fragmented sleep. Those affected have early morning awakening that leads to poor concentration and irritability. It hampers job performance and slows reaction time.
Your doctor might have you complete a questionnaire to determine your sleep-wake pattern and daytime sleepiness. You may be asked to keep a sleep diary.
• How often do you have insomnia and when did it begin?
• How long does it take you to fall asleep?
• How many hours do you sleep?
• Do you snore or wake up choking for breath?
• How often do you awaken at night? How long does it take you to fall back to sleep?
• Are you refreshed when you wake up?
• Are you tired during the day?
• Do you doze off or have trouble staying awake while sitting or driving?
• Where do you sleep? What's the noise level, temperature and amount of lighting?
• Stressful life events?
• Alcohol and tobacco use?
• Family history of sleep issues?
• Recent travel and time changes?
• Long work hours, shift changes, and night shift?
Keep a current list of medications, vitamins, and herbal supplements, including doses. Have your sleep partner come along for your next doctor’s visit. The partner could provide observations that verify information. Your doctor could suggest an overnight sleep study. A blood test might be appropriate to rule out hypo or hyperthyroidism. .
Parkinson’s Disease and Alzheimer’s aggravate symptoms. Ritalin, prescribed for Attention Deficit Syndrome, inhibits sleep. Coffee, tea, and “energy drinks” are detrimental. Other sleep-related disorders include Sleep Apnea and Restless Legs Syndrome. Other disorders include depression, anxiety disorder, post traumatic stress disorder, and substance abuse.
If the cause isn't clear, or you have symptoms and signs of another sleep disorder, such as sleep apnea or restless legs syndrome, referral to an overnight sleep center is recommended. This study monitors brain waves, breathing, heartbeat, brain waves, eye movement, and body movement.
Behavior therapies are recommended as the first line of treatment for those with insomnia. They are equally or more effective than sleep medicines. Cognitive behavioral therapy helps or eliminates negative thoughts and worries that inhibit sleep, such as the concept, “a bad sleep night will make me sick.”.Muscle relaxation, biofeedback and deep breathing reduce anxiety. These modalities bolster breathing, heart function, muscle tension and mood.
“Stimulus control” is a technique that limits time spent awake in bed. The bed and bedroom should only be associated with sex and sleep. Sleep restriction decreases time spend in bed, causing partial sleep deprivation. This strategy creates fatigue the next night. When sleep quality has improved, time in bed is decreased. Other treatments include remaining awake. Also called “paradoxical intention,” this method reduces worry and anxiety about being able to sleep by getting in bed and trying to stay awake, rather than expecting to fall asleep.
If you fall asleep too early and awaken too early, you can use light to push back your internal clock. Go outside during times of the year when it's light outside in the evenings. Consider purchasing a medical-grade light box kept in your bedroom.
Prescription sleeping medicines, such as zolpidem (Ambien), zopiclone (Lunesta), zaleplon (Sonata) or ramelteon (Rozerem) can induce sleep. Physicians might not recommend “prescription sleeping pills” for more than a few weeks.
Over the counter nonprescription sleeping medicines contain antihistamines that cause drowsiness. These reduce sleep quality. Side effects include daytime sleepiness, urinary retention, dry mouth and confusion.
Antihistamines worsen urinary problems, causing urinary urgency during the night. Additional options include Melatonin. This over-the-counter (OTC) supplement could reduce insomnia.
Valerian is a dietary supplement sold as a sleep aid. It has a sedating effect, but hasn't been well studied. It is released into the bloodstream at dusk and tapers off in the morning. You might want to discuss it with your doctor. Those who take it at high doses or long term may develop liver inflammation (hepatitis). When it's time to stop, it should be tapered to prevent withdrawal symptoms.
Stick to a sleep schedule. Keep your bedtime and wake time consistent, including weekends.
Avoid large meals before bed. A light snack is fine. Drink less before bedtime so that you won't have to urinate as often.

Don’t work or eat in bed. Avoid TV, computers, video games, smart phones or other gadgets before bedtime.

The TV and an i-Pad may interfere with your sleep cycle.

Close the bedroom door or create a subtle background noise, such as a fan, to dampen noise sources. You might want to silence your cell phone and bedroom clocks.

A warm bath or massage can prepare you for sleep. Create a relaxing bedtime ritual, such as reading, soft music, breathing exercises, yoga or prayer. Avoid trying hard to sleep. The more you try, the more awake you’ll become.

Read in another room till you’re drowsy, then go to bed to sleep. If you can't sleep after twenty minutes, do something relaxing, such as reading. Try again.

Yoga and Tai-Chi help with sleep quality. Start slow and work with a coach or instructor who listens to your needs and limitations.
“Mindful Meditation” along with conventional treatment can improve sleep. Research suggests that regularly practicing meditation reduces stress and lowers blood pressure.

Source: MayoClinic.org
―
Famous quote: “The best cure for insomnia is to get a lot of sleep.” W.C. Fields

Thursday, March 12, 2015



 
             Alcohol use among active military and veterans is a major health issue.
Throughout military history, holding one’s liquor has been akin to a “real soldier, on par with knowing how to handle one’s weapon. Heavy drinking glamorized the culture of those serving in uniform. Following active duty, veterans who served abused alcohol. Post-Traumatic Stress Disorder was linked to battlefield experience.

            Alcohol causes cancers of the esophagus, mouth, pancreas, larynx, and liver. There is no risk-free level. The more alcohol a person drinks, the higher the cancer risk. Alcoholic beverages contain at least fifteen cancer-causing compounds. These include acetaldehyde, acrylamide, aflatoxins, arsenic, benzene, cadmium, ethanol, ethyl carbamate, formaldehyde, and lead. The most toxic alcohol product is acetaldehyde.

            The fine cilia of the esophagus can be be destroyed by high alcohol concentrations in “hard liquor”. Smoking has long been established as a cancer risk factor. Heavy smoking combined with heavy liquor is especially dangerous. 

            The rate of ethanol metabolism is determined by genetics. Ingested ethanol is changed to acetaldehyde, present in alcoholic beverages. Over time, acetaldehyde can cause cancer of the throat, pharynx, mouth, esophagus, and larynx. Alcohol interacts with folate metabolism and inhibits nutrient absorption from the gut. Poor absorption interacts with ethanol to impair DNA. Alcohol increases estrogen levels, which stimulate cell growth. Other cancer mechanisms include production of reactive oxygen, nitrogen, and tobacco use. The mouth, intestines, liver, and esophagus have the greatest risk for alcohol related cancer. 

            Avoiding alcohol could prevent up to eighty percent of oral and ninety percent of larynx cancer cases. Those who have health problems related to alcohol should quit all forms of use. Warning labels should convey risks associated with alcohol in simple language. Reduction of alcohol consumption is the cost-effective way to reduce disease.

            The more alcohol is consumed in any country, the more alcohol-related diseases occur. Price and availability are tools to decrease consumption. Price is regulated by taxation. Drunk-driving policies and health service measures have some effect. Health information campaigns are valuable for control measures. A return to prohibition isn’t necessary. Increased public awareness would reduce risk. Patients should be informed and concerned about overall risk. Here are strategies to reduce cost and disease burdens. 

Monitor your alcohol intake ("know your number"). This is similar to knowing your blood pressure, weight, Body Mass Index, cholesterol level, blood sugar, and calorie intake. Limit alcohol consumption to twenty grams per day for men and fifteen for women. This is about one and a half drinks for men and one drink for women.  
Less is more. Lower alcohol consumption leads to better health and longer lifespan.
Take a day off. Avoiding alcohol for one to two days weekly lowers risk.